Deliver optimally balanced successful compounds, fast

StarDrop™ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process.

How does StarDrop support your hit-to-candidate process?

Try StarDrop

Easy SAR analysis

Instantly understand and explore the structure-activity relationships in your chemical series.

Aminotetraline matched pairs neighbourhood

Clear data visualisation

Generate interactive charts, graphs and chemical spaces to better comprehend your data.

SAR plot

Multi-parameter optimisation

Find compounds with the best balance of activity, ADME and physicochemical properties.

StarDrop oral CNS scoring profile

Intuitive Card View®

A unique approach to visualising the relationships within your compounds and chemical series.

Compounds can be grouped by cheical similarity as shown on these Card View stacks, so that property trends and patterns in chemical series can be identified

Dynamic Glowing Molecule™

Explore structure-property relationships with instant visual feedback on your optimisation strategies.

The Glowing Molecule, highlighting regions of your structure with a positive or negative impact on a particular property

Seamless AI insights

Leverage the unique capabilities of our Cerella AI platform directly from within StarDrop to reveal transformative insights.

A pipeline of Cerella case studies applied to different parts of the discovery process

Tailored to you

Access a huge range of customisation and integration options to build the workflow you need. Plug-in modules for in silico modelling, generative chemistry or 3D design; collaborative drug design extensions; in-house and external database integration. Whatever you need for your workflow, StarDrop can help.

We’re delivering trust

Thank you to some of our StarDrop users, listed below, who testify to the usefulness of the platform

UCB logo Logo Cerevance Evotec logo Grünenthal logo Novalix logo Arrakis Logo DongBangFTL logo Delfia logo

Discover StarDrop Modules

ADME QSAR

High quality predictive QSAR models of a broad range of key ADME and physicochemical properties

Explore ADME QSAR

Metabolism

Quickly identify metabolic pathways, potential metabolites and guide compound design to avoid metabolic liabilities

Explore our Metabolism Module

Derek Nexus

Knowledge-based prediction of over 40 key toxicity endpoints, helping guide the design of safe, efficacious drugs

Explore Derek Nexus

Auto-Modeller

Build and validate robust QSAR models tailored to your chemistry and data, in an easy and intuitive way

Explore Auto-Modeller

In silico modelling

ADME QSAR

High quality predictive QSAR models of a broad range of key ADME and physicochemical properties

Explore ADME QSAR

Metabolism

Quickly identify metabolic pathways, potential metabolites and guide compound design to avoid metabolic liabilities

Explore our Metabolism Module

Derek Nexus

Knowledge-based prediction of over 40 key toxicity endpoints, helping guide the design of safe, efficacious drugs

Explore Derek Nexus

Auto-Modeller

Build and validate robust QSAR models tailored to your chemistry and data, in an easy and intuitive way

Explore Auto-Modeller

Generative chemistry

Nova

Generate and prioritise new, relevant compound ideas using virtual library enumeration and generative chemistry

Explore Nova

BIOSTER

Access a world of chemistry experience, extending Nova’s capabilities with over 29,000 structure modifications and replacement techniques

Explore BIOSTER

Inspyra

Combine your expert chemistry knowledge and the exploratory power of generative methods to identify optimal compounds faster

Explore Inspyra

Linking 2D and 3D SAR and design

eSim3D

3D ligand-based design – understand binding conformations to identify and optimise novel active compounds

Explore eSim 3D

SeeSAR

3D structure-based design – visualise ligand and protein structures and identify key interactions driving binding affinity

Explore SeeSAR

MPO Strategy

MPO Explorer

Develop multi-parameter optimisation strategies using patented rule induction and sensitivity analysis methods

Explore MPO Explorer

Supporting customisation and collaboration

Idea Tracker

Accelerate your drug discovery projects with collaborative design, centralised sharing and informed decision-making.

Learn more about Idea Tracker

collaborative drug design with idea tracker

Customisation and Integration

Comprehensive data analysis, visualisation and design, easily integrated into your informatics infrastructure.

StarDrop’s customisations and integrations

3D docking and Alignment

Integrated access to 3D modelling to analyse SAR, identify potential liabilities and guide compound design.

StarDrop’s Pose Generation Interface

Database Access

Seamlessly connect to your in-house databases, with a user-friendly interface to access the latest and most relevant data.

StarDrop database access

Understand your structure-activity relationships in 3D

Flexible Deployment

Enjoy identical functionality and user experience, with options for desktop or cloud-based StarDrop, and several hosted server options. 

“StarDrop is a very compelling package- multiple powerful tools combined into a single piece of software accessed via a very intuitive user interface. Viewing biological data and compound properties via card view offers a unique and visually appealing way to interrogate SAR trends. The ease with which powerful MPO scoring functions and QSAR models can be generated and applied to new ideas, as well as the ability to predict metabolic liabilities make StarDrop the go to software for ensuring project progression.”

Dr Robert Pace, Medicinal Chemist, Evotec UK

Interested in trying StarDrop?

Get in touch with the team to discuss your specific projects and needs, and book a software demo.

Get in touch

StarDrop resources

Ready to transform to data-driven decision making?

Simply complete and the team will be happy to have a chat or provide a demo dependent on your specific needs.