Why should medicinal chemists use software?
What exactly is a medicinal chemist’s role today? Firstly, let’s define a medicinal chemist’s role – to design and synthesise…
Shorter development cycle, bigger impact: What’s new in StarDrop™ 8.1
It feels like only yesterday that we announced the arrival of StarDrop 8. And here we are again. Though this time, that’s rather the point. Discovery teams need to iterate quickly, moving from hypothesis…
How leading discovery teams find better compounds, faster
Download the guide and learn what generative chemistry is, where it fits in the discovery workflow, and best practices to avoid common pitfalls.
How can I predict binding affinity without a target protein structure?
Why traditional ligand-based QSAR methods have fallen short You might be sceptical about ligand-based QSAR approaches; many researchers are. We discussed why there has…
How is AI transforming drug discovery chemistry?
Imagine you’re trying to find the correct key to unlock a treasure box, but there are billions of keys to…
Ensemble-based conformational modelling for macrocycles
From X-ray refinement to lead optimisation Conventional ligand-fitting and refinement methods in X-ray electron density maps often yield models with…
Share your science, not your secrets: How StarDrop 8 supports collaboration with CROs
The collaboration challenge: Where generic tools fall short Several collaboration platforms have been designed to support molecule design and optimisation.…
How much does drug discovery software cost?
How number of users affect drug discovery software costs The number of people who need access to the platform is…
Looking beyond statistics: How do I determine whether a QSAR model will add value to my project?
Good statistics don’t guarantee good applicability. Performance metrics will tell you how well a QSAR model predicts known data, but they don’t tell you whether it will add practical value…
