StarDrop Modules

Select from a range of optional plug-in modules

StarDrop offers an extensive selection of plug-in modules that enhance its core capabilities. These modules include predictive models for ADME properties, phase I and II metabolic routes and toxicity, automatic QSAR model building, 3D SAR analysis, and de novo design. By incorporating these modules, users can efficiently explore new optimisation strategies and drive their search for improved outcomes.

In silico Modelling


High quality predictive QSAR models of a broad range of key ADME and physicochemical properties

Derek Nexus

Knowledge-based prediction of over 40 key toxicity endpoints, helping guide the design of safe, efficacious drugs

Metabolism module cover image


Quickly identify metabolic pathways, potential metabolites and guide compound design to avoid metabolic liabilities


Build and validate robust QSAR models tailored to your chemistry and data, in an easy and intuitive way.

De novo Design


Generate and prioritise new, relevant compound ideas using virtual library enumeration and generative chemistry


Access a world of chemistry experience, extending Nova’s capabilities with over 29,000 structure modifications and replacement techniques


Combine your expert chemistry knowledge and the exploratory power of generative methods to identify optimal compounds faster.

Linking 2D and 3D SAR and Design

Surflex eSim3D

3D ligand-based design – understand binding conformations to identify and optimise novel active compounds


3D structure-based design – visualise ligand and protein structures and identify key interactions driving binding affinity

MPO Strategy

MPO Explorer

Develop multi-parameter optimisation strategies using patented rule induction and sensitivity analysis methods