StarDrop Modules
Select from a range of optional plug-in modules
StarDrop offers an extensive selection of plug-in modules that enhance its core capabilities. These modules include predictive models for ADME properties, phase I and II metabolic routes and toxicity, automatic QSAR model building, 3D SAR analysis, and de novo design. By incorporating these modules, users can efficiently explore new optimisation strategies and drive their search for improved outcomes.
In silico Modelling
ADME QSAR
High quality predictive QSAR models of a broad range of key ADME and physicochemical properties
Derek Nexus
Knowledge-based prediction of over 40 key toxicity endpoints, helping guide the design of safe, efficacious drugs
Metabolism
Quickly identify metabolic pathways, potential metabolites and guide compound design to avoid metabolic liabilities
Auto-Modeller
Build and validate robust QSAR models tailored to your chemistry and data, in an easy and intuitive way.
De novo Design
Nova
Generate and prioritise new, relevant compound ideas using virtual library enumeration and generative chemistry
BIOSTER
Access a world of chemistry experience, extending Nova’s capabilities with over 29,000 structure modifications and replacement techniques
Inspyra
Combine your expert chemistry knowledge and the exploratory power of generative methods to identify optimal compounds faster.
Linking 2D and 3D SAR and Design
Surflex eSim3D
3D ligand-based design – understand binding conformations to identify and optimise novel active compounds
SeeSAR
3D structure-based design – visualise ligand and protein structures and identify key interactions driving binding affinity
MPO Strategy
MPO Explorer
Develop multi-parameter optimisation strategies using patented rule induction and sensitivity analysis methods