Is it possible to create my own custom models and data processing algorithms within StarDrop?
Yes, StarDrop allows you to either create your own model/data-processing-algorithm or to integrate one from a third-party application into StarDrop…
I cannot access my application; it asks me to update my password, and the screen does not update
This might be due to the internal firewall blocking the connection to the browser address. Please check with your IT…
Which Operating system does StarDrop run on?
The StarDrop client is supported on the following operating systems: For further information/details, please contact support@optibrium.com.
How do I select compounds?
To select compounds, click on the structure or on the row number in the data table. To select multiple compounds,…
How do I perform an R-group analysis?
When exploring a chemical series, it can be very useful to visualise trends in potency and other properties using SAR…
How do I cite StarDrop in my publications?
You can cite the latest version of StarDrop using the text below: StarDrop v. XXX, Optibrium Ltd; optibrium.com/products/stardrop/ You can…
How do I select compounds with the ‘Make Selection’ tool?
To choose which compounds to select, there is a Selection tool which enables the user to make selections based on…
A practical guide to implementing AI
In this ebook, you’ll discover the key considerations which every leader needs to take in order to successfully implement AI in their drug discovery pipelines.
Shen HIA models
Access Shen HIA Models for robust predictions of human intestinal absorption. Improve drug development. Download now for enhanced bioavailability insights.
PAINS Model
Baell and Holloway published a set of substructure filters for removal of what they termed “Pan Assay Interference Compounds (PAINS)” from…
HTS promiscuity alerts model
Screen for HTS promiscuity with StarDrop HTS Promiscuity Alerts.
Heavy atom count
Determine heavy atom count effortlessly with StarDrop Heavy Atom Count tool. Download now for precise molecular analysis and property estimation.
Topological Polar Surface Area – Including S and P
In J. Med. Chem., 2000, 43 (20), pp 3714–3717, Ertl et al. propose the calculation of two polar surface area values, the first reports the PSA…
Exact mass calculator
This model calculates the “exact mass” of a molecule based upon the masses of the most abundant isotopes of its…
HLM stability models
StarDrop™ HLM Stability Models are courtesy of Alexey Zakharov of the National Cancer Institute, National Institutes of Health, who has developed models of stability in Human liver Microsomes (HLM)
Do the ADME models learn from our data?
No, StarDrop’s ADME QSAR model will not learn from your data. However, if you want to build ADME models based…
Some of my P450/Metabolism calculations are not returning results. The Metabolism results are returned but not the full analysis.
Some compounds do take much longer than others and this is due in part to the number of possible conformations…
How synthesisable are the molecules proposed by StarDrop’s Nova module?
The Nova ideas generated depend on the parameters set by users’ input, which are based on over 200 commonly known…
How do you assess chemical similarity?
Chemical similarity is assessed by calculating similarity for pairs of molecules using 2D path-based fingerprints and the Tanimoto similarity index.…