Matched Series for SAR Analysis
Try Matched Series Analysis in this follow-along tutorial
Viewing a series of compounds aligned in 2D is important when analysing structure-activity relationships. Differences in structure are easier to identify, and it can help you explore key parts of the structure that influence activity and other properties.
Using the structure alignment tool in StarDrop, you’re able to define a substructure to perform a rigid alignment of molecules in the data set. By consistently aligning data sets with multiple scaffold chemotypes, visualisation of functional group variations around a common scaffold and SAR elucidation is facilitated.
This quick video demonstrates the structure alignment tool in action.
More SAR resources</span?
From similarity to SAR
In this webinar, we present a flexible and intuitive framework in which similarity relationships can be interactively navigated to quickly interpret the results, identify important structure-activity relationships (SAR) and use that SAR in new compound design.
Information rich SAR plots
This short video illustrates how to create information rich SAR plots, including pie charts, histograms, scatter plots, radar plots, etc.…
