This article discusses Quantitative Structure – Activity Relationships (QSAR) methods to predict Absorption, Distribution, Metabolism, Excretion and Toxicity (ADMET) properties.
It covers statistical modelling techniques, molecular descriptors and data sets used for model building, alongside the application of predictive ADMET models in drug discovery, and challenges faced.
J. M. Gola, O. Obrezanova, E. Champness, M. D. Segall, QSAR Comb. Sci., 2006, 25(12), pp. 1172 – 1180
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