R-group matched pairs
This short video illustrates how to perform Matched Molecular Pair Analysis (MMPA) within a chemical series using StarDrop’s R-group analysis tool. This…
When exploring a chemical series, it can be very useful to visualise trends in potency and other properties using SAR tables. This worked example illustrates how you can quickly and easily perform R-group decompositions and plot SAR tables in StarDrop.
You can find a short video demonstrating this example in our online community at R-group analysis – Optibrium.
If you have anything specific you want to do with the R-group analysis tools, please contact us at support@optibrium.com.
More SAR resources
Single-scaffold R-group analysis
In this quick example, we will look at a single-scaffold R-group analysis to identify any functionalities which are influencing potency. The data…
R-group clipping of reagents for library enumeration
In this example, using StarDrop’s R-group clipping tool, we will quickly transform chemical building blocks into their corresponding substituents, ready to enumerate a virtual library in StarDrop’s Nova module.
