R-group decomposition
StarDrop’s R-group analysis makes it quick and easy to explore the variation of properties by the substituents within a chemical series. This…
In this example we look at R-group analysis of chemical series to identify key functionalities which influence potency.
One example looks at a series of analogues of Buspirone and a second uses a multi-scaffold R-group analysis to analyse SAR across two scaffolds with equivalent substitution points.
Would you like to try it yourself?
To try this example yourself, download the example project file and follow the step-by-step guidelines.
Please note that the tutorial explores core features of StarDrop. If you don’t have access to this module and would like to arrange a trial, please email us at info@optibrium.com
More SAR resources
Information rich SAR plots
This short video illustrates how to create information rich SAR plots, including pie charts, histograms, scatter plots, radar plots, etc.…
R-group matched pairs
This short video illustrates how to perform Matched Molecular Pair Analysis (MMPA) within a chemical series using StarDrop’s R-group analysis tool. This…
Single-scaffold R-group analysis
In this quick example, we will look at a single-scaffold R-group analysis to identify any functionalities which are influencing potency. The data…
