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Small Molecule Drug Discovery & Data Visualisation

A complete platform for small molecule design,
optimisation and data analysis

DELIVER OPTIMALLY BALANCED

Successful Compounds, Fast

With its comprehensive suite of integrated software, StarDrop™ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDrop™ enables a seamless flow from the latest data through predictive modelling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process.

QUICKLY IDENTIFY

Effective Compounds

Successful compounds require a balance of many different properties. StarDrop™ guides you through this multi-parameter optimisation challenge to target compounds with the best chance of success, saving you time and resources by enabling you to synthesise and test fewer compounds.

Make Decisions with Confidence

Take into account the inherent uncertainty in discovery data to avoid missing valuable opportunities.

Optimise Your Compounds

Highlight key structure-activity relationships that guide the design of improved efficacy.

Flexible Integration

Connect seamlessly with your models, informatics methods and database, providing user-friendly access to these resources, to make project management quicker and simpler.

Cerella™ Integration

Leverage the unique capabilities of Cerella AI discovery data platform directly from within StarDrop.

WITH A RANGE OF

Plug-in Modules

StarDrop’s™ core features can be extended with a comprehensive range of optional plug-in modules; predictive models for ADME properties, Phase I and II metabolic routes and toxicity; automatic QSAR model building; 3D SAR analysis; and de novo design to stimulate the search for new optimisation strategies.

Metabolism

Quickly identify metabolic pathways, potential metabolites and guide compound design to avoid metabolic liabilities.

Derek Nexus

Knowledge-based prediction of over 40 toxicity endpoints

ADME QSAR

High quality predictive QSAR models of key ADME properties

Auto-Modeller

Build and validate robust QSAR models tailored to your chemistry and data

Nova

Generate & prioritise new, relevant compound ideas

BIOSTER

A world of chemistry experience

Inspyra™

Inspyra™ combines your expert chemistry knowledge and the exploratory power of generative methods to help you identify optimal compounds faster.

Surflex eSim3D

3D ligand-based design – understand binding conformations to identify and optimise novel active compounds

SeeSAR

3D Structure-based design

MPO Explorer

Develop multi-parameter optimisation strategies

A DYNAMIC RANGE OF

Core Features

Multi-parameter Optimisation

Rigorously assess your compounds’ potential for success against your project objectives

Interactive Design with the Glowing Molecule™

Highlight the regions of your compounds which have the greatest influence on predicted properties to guide the design of high-quality compounds.

SAR Analysis

Instantly understand and explore the structure-activity relationships in your chemical series.

Data Visualisation with Card View®

View multiple, interactively linked charts simultaneously and work more flexibly with Card View to explore the relationships between properties and compound structures and guide further optimisation.

StarDrop Card view feature
StarDrop Monitors 2023

COMPREHENSIVE SUITE OF

Integrated Software

StarDrop integration screenshot

Customisation and Integration

StarDrop’s comprehensive data analysis, visualisation and compound design environment has been built to work seamlessly with your informatics infrastructure.

Dock and alignment feature of StarDrop drug visualisation software

Docking and Alignment

Seamless access to 3D modelling

Database access feature of StarDrop drug visualisation software

Database Access

Seamless connection with your in-house databases

STARDROP™ IN ACTION

Rapid Focus in Lead Optimisation

The application of StarDrop™ to this project could have resulted in a 90% saving in compounds synthesised. No in vitro ADME screens were used in the selection process and, furthermore, a 70% saving in in vivo testing was achieved to reach the same endpoint.

Rapid focus case study

WOULD YOU LIKE TO TRY STARDROP™?

Get In Touch

To trial StarDrop please complete the form and a member of the team will get in touch to understand your needs and get you set-up with a licence that works best for you.