Bring your data into StarDrop
Data Import: It’s easy to import your data into StarDrop. Many people start by loading a data file. StarDrop supports many standard data formats (including CSV, SDF, and MOL2). This short video shows you how to open your data files in StarDrop, with links to other resources for merging, filtering, and managing your data sets to make sure you’re always working with your most current data.
Database Integrations: If you work with CDD Vault or Certara D360, we have direct integrations to those data management platforms that can help you to query and load your data. If this is something that you’d like to try, contact our support team and we’ll be happy to help you get started.
Query Interface: If StarDrop is directly connected to your in-house database, then you can use StarDrop’s Query Interface to seamlessly connect to your in-house database and use the user-friendly interface to access the latest and most relevant data. This video shows you how to build and run queries in the Query Interface.
Visualise and analyse your data
StarDrop has a wide variety of powerful and intuitive options for data visualisation to help you analyse your data and make confident decisions that guide your project.
Charts and Visualisations: Quickly make information-rich visualisations to understand key relationships in your data. Explore our series of short videos that demonstrate how to create and customise compelling visualisations.
Card View®: Use Card View to break free from the confines of traditional spreadsheets to view and analyse your data in the way that you think – in terms of compounds, series and relationships! This short video introduces Card View with links to examples of other ways you can use Card View to analyse SAR on your project, including clustering, matched molecular pairs, and activity landscapes
Structure-Activity Relationships (SAR): StarDrop includes flexible methods for R-group decomposition and SAR analysis, so you can easily pinpoint the best chemistry to explore. This video shows how to perform an R-group decomposition analysis and links to other ways you can visualise and analyse your SAR.
Interactively explore compound optimisation and design
StarDrop provides unique capabilities for guiding your design of new and improved compounds.
Multi-Parameter Optimisation (MPO): Discovery scientists need to optimise against multiple potency, ADME and safety criteria. In StarDrop you can define a Target Product Profile that describes the ideal outcome for your project and use it to quickly identify the compounds most likely to succeed in your project. This video introduces you to StarDrop’s Probabilistic Scoring approach to multi-parameter optimisation (MPO), with links to other MPO resources. Start with one of our built-in MPO templates or build your own!
Interactive Design: Use StarDrop’s Glowing Molecule™ to visualise the structure-activity relationships captured by the ADME and toxicity models available in StarDrop’s ADME QSAR module to understand where to design changes in your compounds and guide the design of compounds with an improved balance of properties. You can find examples of using the Glowing Molecule in our tutorial videos linked below.
Use our tutorials to quickly master new features
We have a wide range of quick tips and worked examples to help you become familiar with StarDrop and its modules. We recommend that you start with our hit-to-lead tutorial, which walks you through a hit list triage, lead optimisation and design workflow covering many of the core features of StarDrop. Data sets and step-by-step instructions are provided with each tutorial.
We also have tutorials to help you explore any of the optional modules you license:
Save and share your work
After working in StarDrop, it’s important to save and share your analysis.
Save Projects and Data: Everything that you have been working on within StarDrop at any one time is part of a single project. From the File menu, choose Save Project to save a project. All data sets, visualisations, dashboards, scoring profiles, summary analyses, functions, and Card View templates will be saved with the project enabling you, the user, to save, restore and share complete StarDrop sessions.
You can also save the data from a StarDrop Project (including the statistics for each value). From the File menu, choose Save Data Set As, and the Save As dialogue will appear. Specify the file name where prompted, choose the export file type, and click the Save button.
Export to PowerPoint or Excel: This short video illustrates how you can simply copy selected compound identifiers, structures and any data directly from StarDrop and instantly create summary tables within Excel, Word, PowerPoint, etc. to present and share your results.
If you’re accessing StarDrop through your web browser, please follow the hints in this video to download your images and data from our hosted AWS environment.
Get the support you need, when you need it.
Our team of dedicated application scientists are here to provide expert training and support. Whether you have questions, challenges, or just want to explore what’s possible, don’t hesitate to reach out. Before long, they’ll feel like part of your team.
I have to say the support team have been excellent. Whenever I have a question, I don’t like to
Sébastien Alazet, Medicinal chemist
wait.
adMare Bioinnovations
Contact our support team to schedule training
Use the form below or contact support@optibrium.com with any questions or to schedule training. We look forward to hearing from you!