Tutorials

R-Group Analysis

May 18, 2022

R-Group Analysis

May 18, 2022

In this example we look at R-Group analysis of chemical series to identify key functionalities which influence potency. One example looks at a series of analogues of Buspirone and a second uses a multi-scaffold R-group analysis to analyse SAR across two scaffolds with equivalent substitution points.

To try this example yourself, download the example project file and follow the step-by-step guidelines in this PDF.

Please note that the tutorial explores core features of StarDrop. If you don’t have access to StarDrop and would like to arrange a free trial license, please email us at info@optibrium.com

Please note that this video was recorded with an earlier version of StarDrop, so there may be small differences in appearance, however the process demonstrated is unchanged.

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