In this example we look at R-Group analysis of chemical series to identify key functionalities which influence potency. One example looks at a series of analogues of Buspirone and a second uses a multi-scaffold R-group analysis to analyse SAR across two scaffolds with equivalent substitution points.

To try this example yourself, download the example project file and follow the step-by-step guidelines in this PDF.

Please note that the tutorial explores core features of StarDrop. If you don’t have access to StarDrop and would like to arrange a free trial license, please email us at [email protected]

You can also watch a video of this tutorial here, others that might interest you can be found in the tutorials section of our video archive.

_{Please note that this video was recorded with an earlier version of StarDrop, so there may be small differences in appearance, however the process demonstrated is unchanged.}