To start a virtual screening experiment, click the arrow button menu
Run Virtual Screen.

Several options are available to load the 3D input structure(s) to use for virtual screening:
Open a file containing the 3D coordinates by clicking the
button.
Download a PDB containing the molecule in a bioactive conformation by clicking the
button.
Use an entire bunding hypothesis or obtain a molecule in a specific conformation from a binding hypothesis result by clicking the
button.
Use a compound in the 3D Viewer by selecting all atoms of the molecule and clicking the
button.
Once the desired input conformations have been selected, click Next.
In the next page of the wizard, you can Choose a virtual screening database.

Load the virtual screen collection by clicking on
button, locate where you saved the files and confirm it.
For more details, please refer to the StarDrop user guide.