About the position

As we continue to grow and innovate, we are seeking a skilled Research Scientist to join our dynamic Research Team. This is an exciting opportunity for a scientist with experience of 3D molecular modelling to contribute to the development of state-of-the-art software and AI solutions that are transforming the field of small molecule discovery. Help us drive forward groundbreaking advancements in science and technology. 

If you want to make a difference in the discovery of new medicines through the use of the latest machine learning and computational chemistry methods we have a great opportunity for you to contribute to growing our success in translating peer-reviewed scientific research into successful products. We are looking for a Research Scientist to work with customers, collaborators and colleagues to apply deep learning methods to challenges in drug discovery

Key responsibilities

  • Apply 3D structure- and ligand-based design methods to pharmaceutical lead discovery and optimization, particularly in the field of complex peptidic macrocycles, supporting current and potential customers’ effective use of our BioPharmics platform  
  • Use NMR and X-ray crystallography data in combination with BioPharmics’ 3D molecular modelling methods to achieve excellent results  
  • Work closely with our commercial team to communicate the value of the BioPharmics platform in a clear and scientifically accurate way to potential customers  
  • Provide guidance on the further development of the BioPharmics platform, identifying our customer’s unmet needs and proposing innovative approaches to their solution  
  • As part of the company’s Research team, participate in a wide range of scientific innovation projects  
  • Represent the company’s scientific innovations and products in a clear and engaging way to the scientific community at conferences and in meetings with current and potential customers  

Ideal requirements

  • PhD in computational chemistry, computer science, chemistry, or biophysics  
  • Practical experience in applying 3D molecular modelling to pharmaceutical lead discovery and optimization, including knowledge of PyMOL, MOE, Maestro, and other modelling platforms  
  • A track record of high-quality peer-reviewed publications and conference presentations 

What We Offer

We offer hybrid & flexible working, a competitive base salary, pension contribution, employee private medical cover, life insurance, gym membership assistance, cycle to work scheme, and of course, lovely colleagues!  

We are a growing technology company dedicated to providing elegant software solutions for drug discovery. Optibrium’s lead product, StarDrop™, is a comprehensive suite of integrated software that guides small molecule design, optimisation, and data analysis, improving the speed, efficiency, and productivity of the discovery process. The company’s new Augmented Chemistry® products and services deliver ground-breaking artificial intelligence technologies that continuously learn from all available data to supplement researchers’ experience and skills.  

If you’re interested in joining a growing, entrepreneurial team working in an exciting field, please apply with a CV and covering letter to vacancies@optibrium.com.