by Marina Chenery | Jan 15, 2021
Case Studies Neglected Diseases Drug Space This ‘drug space’ was generated using StarDrop’s drug discovery chemical space visualisation using a set of 1395 marketed small molecule drugs. In this space, the proximity of two points represents the structural...
by Marina Chenery | Jan 15, 2021
Case Studies Cardiovascular Drug Space This ‘drug space’ was generated using StarDrop’s chemical space visualisation using a set of 1395 marketed small molecule drugs. In this space, the proximity of two points represents the structural similarity between...
by Marina Chenery | Oct 6, 2020
Case Studies Drug Constellations Drug Constellations Optibrium’s drug constellations provide an instant, visual summary of important small-molecule drugs for a therapeutic class or indication. Ten drugs for each indication are mapped across the ‘chemical space’ of all...
by Marina Chenery | Oct 6, 2020
Case Studies User-friendly database querying Value Seamless connectivity between design and decision making tools and the data management system ensures that project teams have access to the latest information without needing to compile the data manually from many...
by Marina Chenery | Oct 6, 2020
Case Studies Balancing properties in lead optimisation Value Parallel optimisation is essential to developing compounds with the correct balance of properties. In this study, we identified four compounds that had been overlooked by traditional compound selection based...