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Paper Highlights Key Challenge in Applying Models
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Paper Highlights Key Challenge in Applying Models
matt
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A new paper, "Making Priors a Priority", by Matt Segall of Optibrium and Andrew Chadwick of Tessella addresses a key challenge the community needs to address to get the most out of the predictive models we build. Just published on-line in J. Comp. Aided Mol. Design (DOI 10.1007/s10822-010-9388-7), the paper discusses the question, "How useful will a model be in making a decision in a practical context?" To answer this requires an understanding of the prior probability distribution (“the prior”) and hence prevalence of negative outcomes due to the property being assessed.

The full article can be downloaded from the Springer website at http://www.springerlink.com/content/x15h763770611316/ or a free preprint can be found on Optibrium's on-line community.
 
Last Edit: 2014/01/20 04:20 By ejc.
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Matt Segall
CEO, Optibrium
matt.segall@optibrium.com
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