by Marina Chenery | Feb 17, 2016 | StarDrop Tutorials, Tutorials
This worked example considers a publically available set of PPARγ pIC50 data which contains a number of chemical series. Matched Series Analysis is used to identify when a substitution from one series has a high likelihood of improving the binding of another series at...
by Marina Chenery | Nov 28, 2014 | StarDrop Tutorials, Tutorials
Card View™ – Hit List Triage In this example, Card View™ is applied to analyse the results from a kinase project in which a large screening campaign has resulted in a hit list. The project team wish to evaluate the list to identify the chemotypes within and...
by Marina Chenery | Oct 16, 2013 | StarDrop Tutorials, Tutorials
Guiding Selection and Design in Hit-to-Lead The objective in this example is to identify one or more high quality chemistries for progression to detailed in vitro and in vivo studies, based on initial screening data for potency; ideally the compounds chosen for...