R-Group Analysis

R-Group Analysis

R-Group Analysis In this example we look at R-Group analysis of chemical series to identify key functionalities which influence potency. One example looks at a series of analogues of Buspirone and a second uses a multi-scaffold R-group analysis to analyse SAR across...
Matched Series Analysis

Matched Series Analysis

Matched Series Analysis The objective in this worked example is to identify new derivatives that are likely to improve activity at their target, given the SAR already generated on a project. To try this example yourself, download the data file and follow the...