Two Decades under the Influence of the Rule of Five and the Changing Properties of Approved Oral Drugs This paper appeared in Journal of Medicinal Chemistry, September 13, 2018. Abstract Two decades have passed since the rule of five ushered in the concept of...
Antimalarial Lead-Optimisation Studies on a 2,6-Imidazopyridine Series within a Constrained Chemical Space To Circumvent Atypical Dose−Response Curves against Multidrug Resistant Parasite Strains This paper appeared in Journal of Medicinal Chemistry, September 26,...
High-Quality Hits from High-Throughput Screens This paper appeared in Genetic Engineering & Biotechnology News, October 15, 2018. Abstract When analysing the results from a high throughput screening (HTS) campaign the goal is to identify diverse hit series with...
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