by Marina Chenery | Oct 16, 2013 | StarDrop Modules and Features, Videos
This short demo introduces StarDrop’s BIOSTER module. The BIOSTER module contains a unique compilation of almost 30,000 precedented bioisostere and bioanalogue transformations that can be used by Nova to generate new compound ideas. If you can’t play the video...
by Marina Chenery | Oct 16, 2013 | StarDrop Modules and Features, Videos
Compound Prioritisation and Selection In this demo we’re going to take a look at how StarDrop can guide the prioritisation and selections of compounds using a combination of in vitro and in silico data. Using StarDrop’s probabilistic scoring, data...
by Marina Chenery | Oct 16, 2013 | StarDrop Modules and Features, Videos
Automatic Generation of New Chemistry Ideas In this demo we take a look at how StarDrop’s Nova plug-in module can be used to generate new compound ideas. Starting with three lead compounds you can see how it is possible to generate new ideas which are optimised...
by Marina Chenery | Oct 16, 2013 | StarDrop Modules and Features, Videos
Addressing Toxicity in Compound Prioritisation and Selection In this demo we’re going to take a look at how toxicity predictions from the Derek Nexus module can be included in StarDrop’s Probabilistic Scoring to intuitively balance the reductions of...
by Marina Chenery | Oct 16, 2013 | StarDrop Modules and Features, Videos
Redesign to Reduce Toxicity Risk In this demo we look at how it’s possible to use the Derek Nexus module with StarDrop to guide the design of new analogues around a compound with predicted toxicity risks using StarDrop’s interactive Drug Design tool. If...