Analysis of High-throughput Screening Data

Analysis of High-throughput Screening Data The following example uses a publicly available set of over 1000 compounds with data from a COX-2 inhibition screen. The example demonstrates different ways to analyse the inhibition data from an HTS campaign to identify high...

Guiding Selection and Design in Hit-to-Lead

Guiding Selection and Design in Hit-to-Lead The objective in this example is to identify one or more high quality chemistries for progression to detailed in vitro and in vivo studies, based on initial screening data for potency; ideally the compounds chosen for...